The LifeBox project, developed at IISc Bangalore, aims to address the critical shortage of donor hearts for transplantation in India. Cardiovascular diseases account for a significant percentage of deaths, with heart transplants being a life-saving procedure. However, only a fraction of patients receive suitable donor hearts due to logistical constraints and limited resources. LifeBox extends the preservation window for donor hearts from the standard 3 hours to 6-8 hours, enhancing the success rate of transplants. The device uses cardioplegia and a cooling system to maintain hypothermic temperatures (4-8°C) while slowing the heart's metabolism. It also incorporates sensors that monitor biomarker data to evaluate the heart’s health during transportation. The project's aim was to improve the user experience by designing intuitive interfaces for medical professionals, making the device user-friendly and accessible. LifeBox has undergone several technical refinements and has been recognized with prestigious awards, including the James Dyson Design Award (2021) and the Lexus Design Award India (2022). Clinical trials and animal studies are currently underway to further enhance the prototype, with the goal of revolutionizing heart transplant procedures and saving lives across India.